Searchable abstracts of presentations at key conferences in endocrinology

ea0020p204 | Endocrine tumours and neoplasia | ECE2009

The variability of clinical presentation of multiple endocrine neoplasia syndrome type 1 as the reason of the underestimated diagnosis

Elwira Elwira , Hubalewska-Dydejczyk Alicja , Pach Dorota , Kuniarzz Sylwia , Tracz Marta

Introduction: Multiple endocrine neoplasia (MEN) is a rare disease. Apart from the well recognised MEN2 syndrome the MEN1 is less common diagnosed. The MEN1 gene is localised on the 11q13 chromosome and encodes menin. There is no simple definition of MEN1 syndrome because of heterogenous combination over 20 different endocrine and non-endocrine tumours. According to the Gubbio consensus, MEN1 is diagnosed by the occurrence of two of the three main MEN1-related endocrine tumour...